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James et al., 2015), that catalyses (phospho)lipid hydroperoxide propagation, using salicylaldehyde isonicotinoyl hydrazone (SIH, 250 M), a lipophilic acylhydrazone that scavenges intracellular iron and mobilizes it for extracellular clearance (Kalinowski and Richardson, 2005)

Nine percent of participants experienced adverse reactions significant enough to require discontinuation of sotorasib