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However, the clinical translation of polyphenols is significantly hindered by poor bioavailability

The indirect antioxidant activity of glutathione is demonstrated by glutathione peroxidase (GPx), which uses glutathione as a reducing agent to catalyze the reduction of H 2 O 2, or organic hydroperoxides to water

Thorax 79 (6), 524537

Sumida K, Molnar MZ, Potukuchi PK, et al

This can cause the estrogen metabolites to be reabsorbed from the intestines and go back into circulation.[ref] Calcium D-glucarate can suppress the beta-glucuronidase activity in the gut, thus increasing the number of estrogen metabolites that are excreted.[ref] Hormone Replacement Therapy: Hormone replacement therapy (HRT) in menopause is the replacement of naturally declining estrogen and progesterone levels with either synthetic or bioidentical hormones