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S., Mahler J., Ragan H

The researchers proposed that the compounds effects on muscle function operate through boosting NAD+ levels by inhibiting NNMTs consumption of nicotinamide, more substrate is available for NAD+ synthesis via the salvage pathway, supporting mitochondrial function and energy metabolism in aged skeletal muscle

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Peer review Peer review information Nature Communications thanks Johannes Huppa, Christian Klein and the other anonymous reviewer(s) for their contribution to the peer review of this work

Carnitine: A building block for proteins and helps the body burn fat as fuel