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Guided by functional annotation (Table 2) and comparison to analogous metabolic systems, the proteins encoded by the mec cassette genes may comprise a DCM catabolic pathway that is compatible with available biochemical evidence (Figure 6)

they have dead ends and are not structured into venules, arterioles, and capillaries, resulting in excessive interstitial pressure

Among the upregulated genes, genes of the oxidative stress pathway seemed particularly absent, instead we found many genes that were 2-fold induced

As cDC1 is well known to be involved in CD8 + T cell priming and activation, we investigated cDC1-deficient Batf3-KO mice

Haiech, J