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From our computations, C283 seems the most likely to covalently bind to omeprazole, since 9 conformations out of 250 showed a strain energy lower than 2 kcal/mol and the best solution had an energy of 29.9 kcal/mol

Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression

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Importantly, animal studies using non-human primates and rodents have also revealed demyelination with age, providing a reliable model for researchers to try and understand the cellular mechanisms at play