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Disclosures: Kenneth Sherman: AbbVie: Grant/Research Support, Gilead: Grant/Research Support, Helio: Grant/Research Support, Intercept: Grant/Research Support, Zydus: Grant/Research Support, NovoNordisk: Advisor, MedPace: Consultant, Pliant: Consultant, Horizon/Amgen: Consultant, Minhee Kang: Nothing to Disclose, Triin Umbleja: Nothing to Disclose, Andrea Cox: Nothing to Disclose, Karen Vigil: Gilead Sciences: Speaking and Teaching, Theratechnologies: Grant/Research Support, ViiV: Advisor, Ngan Ta: Nothing to Disclose, Ayotunde Omoz-Oarhe: Nothing to Disclose, Jennifer Price: Nothing to Disclose, Josphat Kosgei: Nothing to Disclose, Leolin Katsidzira: Nothing to Disclose, Hugo Perazzo: Nothing to Disclose, Kevin Knowles: Nothing to Disclose, Beverly Alston-Smith: Nothing to Disclose, Kristen Marks: Gilead Sciences, Inc: Consultant, Icon: Consultant 371 ROLE OF AIR POLLUTION IN THE DEVELOPMENT OF HEPATOCELLULAR CARCINOMA AMONG CHRONIC HEPATITIS B PATIENTS TREATED WITH NUCLEOTIDE/NUCLEOSIDE ANALOGUES Chia-Yen Dai 1 Tyng-yuan Jang 2 Chih-Wen Wang 1 Chung-Feng Huang 2 Ming-Lung Yu 1 , 1 Kaohsiung Medical University, 2 Kaohsiung Medical University Hospital, Kaohsiung Medical University Background: Hepatitis B virus (HBV) infection is the major cause of hepatocellular carcinoma (HCC)

Nature 572, 205210

After 30 s, the unbound sample was removed by manual blotting with filter paper

Inhibition of mitochondrial fission prevents hypoxia-induced metabolic shift and cellular proliferation of pulmonary arterial smooth muscle cells

Immunofluorescence microscopy Preparation of immunofluorescence samples was performed as described 79