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This discrepancy is expected, and reported events could be because the pharmacokinetics of intravenous methylene blue are different than that of oral methylene blue

In our study, 51 participants who received neoadjuvant therapy were categorized as the sensitive group (patients with pCR and pPR, n = 30) or the resistant group (patients with pNC, n = 21) (Table 2)

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This is because the subtle changes revealed by MRI are often the only objective evidence used to validate the persistent, disabling nature of the injury

[DOI] [PubMed] [Google Scholar] 18.Goligorsky MS, Li H, Brodsky S, Chen J