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Effect of ascorbate or N-acetylcysteine treatment in a patient with hereditary glutathione synthetase deficiency

Wang J-S, Shen X, He X et al (1999) Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by Oltipraz in residents of Qidong, Peoples Republic of China

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However, their contribution is context-dependent, as genetic ablation of ABCC1 does not fully prevent apoptosis-associated GSH loss in certain models 43 , indicating the existence of compensatory or alternative efflux mechanisms