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By modulating the chromatin structure and accessibility of the NRF2 promoter, epigenetic modifications determine how effectively NRF2 can be activated in response to various cellular stresses

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c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1/S-phase transition Mol Cell Biol 1997 17 : 65266536 Ravi R, Mookerjee B, van Hensbergen Y, Bedi GC, Giordano A, El-Deiry WS, Fuchs EJ, Bedi A