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Preclinical findings demonstrate that systemic inflammation induced by maternal obesity and GDM leads to an increased release of maternal proinflammatory cytokines that cross the placenta and alter the fetal development of neural pathways that regulate behavior [69]

Natl Toxicol Program Tech Rep Ser 556:1194 Qadir M, Hussain A, Hamayun M, Shah M, Iqbal A, Murad W (2020) Phytohormones producing rhizobacterium alleviates chromium toxicity in Helianthus annuus L

The involvement of individual P450s in the metabolism of a given drug may be screened in vitro by means of selective functional markers, selective chemical P450 inhibitors, and P450 antibodies

Agonist, Antagonist Binding and Modulation of Bitter Receptors In simple pharmacological terms an antagonist is a ligand that inhibits the biological response induced by an agonist and does not induce any response of its own, while a ligand that reduces the constitutive/basal activity of a GPCR is considered an inverse agonist

He C, Li Y, Gan L, Lin Y, Zhang B, Ma L, et al