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& Kourtidis, A

Avoid : repeated freeze-thaw cycles, exposure to direct light, temperatures above 25C

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

Methylcobalamin, on the other hand, is a naturally occurring form of B12

These modifications are designed to counteract the immunosuppressive tumor microenvironment (TME) by enhancing T-cell activity and survival, thereby directing CAR-T cells towards the tumor site