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In mammalian cells, GCS is a heterodimer consisting of the catalytic heavy-chain subunit (GCS-HS) and regulatory light-chain subunit (GCS-LC) (322)

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Backeljauw P, Cappa M, Kiess W, et al

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This suggests that p53 may exert its protective effects through alternative pathways or mechanisms that do not directly involve NO

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Meex RCR, Watt MJ

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