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The role of acid-base imbalance in statin-induced myotoxicity

doi: 10.1038/s41392-020-0115-0

[DOI] [PubMed] [Google Scholar] Mercader J, Sabater AG, Le Gonidec S, et al

Hb is then oxidized to Hi, heme is liberated from globin & globin denatures producing Heinz bodies

Saponins are surface active compounds having five- or four-ring triterpenes with cardioprotective potential and can be involved in calcium homeostasis, regulation of energy metabolism, inflammation stopping, and oxidative stress