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Furthermore, cellular senescence, apoptosis, inflammatory mediator regulation of TRP channels, renal cell carcinoma, arachidonic acid metabolism, epithelial cell signaling in Helicobacter pylori infection, necroptosis, and Th1 and Th2 cell differentiation mechanisms were also modulated by DSF targets

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Globally, approximately 1% of adults in their 4-6th decades of life suffer from RA [3, 4]

Furthermore, higher sSR-E1 levels are associated with earlier age of SLE diagnosis (108), suggesting that SR-E1 could serve both as a biomarker and a therapeutic target in SLE-related vascular disease

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