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This damage can disrupt the respiratory chain, impair ATP production, and cause a loss of the electrical potential difference across the inner mitochondrial membrane (), a hallmark of mitochondrial dysfunction

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The effect of UV in sunlight on oil can add oxygen molecules to the hydrocarbons as well as interact with polycyclic aromatic compounds (PACs)

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Section 1861(pp)(1)(D) of the Act also authorizes the Secretary to include in the definition of CRC screening tests other tests or procedures, and modifications to the tests and procedures described under this subsection, with such frequency and payment limits, as the Secretary determines appropriate, in consultation with appropriate organizations. 3