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Chida J, Hara H, Yano M, Uchiyama K, Das NR, Takahashi E, Miyata H, Tomioka Y, Ito T, Kido H, et al

These results create a reference point for tracking your progress and ensuring safety throughout treatment

Variability in the results of the molecular imaging studies reviewed may be due to subject samples that may include individuals at risk for AD or who have subjective cognitive complaints, use of clinician rated or self-reported depression outcomes, how cognitive status or depression diagnosis was determined, number of past depressive episodes, antidepressant treatment history, how AD pathology was analyzed (a cutoff of positive/negative or whether quantitative measures were used)

The synergistic application of these strategies is expected to overcome the limitations of single-agent treatment ( Table 1 )

doi: 10.3389/fphar.2022.844961 67 HuangX.HuJ.ZhangH.LiJ.ZhuX.LiuY.et al