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Finally, using MIHA cells as a normal cell model, the synergistic group of CeO 2 MnO 2 and X-ray was confirmed to have a significant protective effect on normal cells by MTT assays

After metabolic pathway analysis, it was found that the antidepressant mechanism of ZZCD on CUMS rats related to the improvement of brain metabolism in Phenylalanine, tyrosine and tryptophan biosynthesis, Glutathione metabolism, Phenylalanine metabolism, Lysine degradation, Cysteine, and methionine metabolism, Tyrosine metabolism, and Tryptophan metabolism