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Till date, eight different isozymes, viz., GPx1-GPx8, have been identified in humans, of which GPx1, GPx2, GPx3, GPx4, and GPx6 are selenoenzymes containing Sec in their active site (Table 1) [1, 8, 9]

Because this is a redox reaction, while glucose 6-phosphate is being oxidized, another molecule must also be reduced

Whole body or tissue-specific knockout of one or several genes is a frequently used approach in mechanistic research

When paired with the ferroptosis process, nanomaterials can improve therapeutic efficacy and demonstrate great promise in targeted therapy

Glutathione is often called the"master antioxidant" due to itsessential role in maintaining oxidativebalance in the body