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In oxidative stress and inflammation triggered by ICH and IVH, mitophagy reduces excessive ROS production, prevents cell apoptosis, and alleviates brain tissue damage [84]

Mn has been shown to exert both beneficial and detrimental effects on endothelial function, depending on its concentration and the specific organ system involved

6 Clinical transformation and prospects 6.1 Diagnostic reagent development Especially in the early diagnosis and risk assessment of diabetes, metabolomics technology has shown great potential in the field of diagnostic reagent development, and its application has gradually entered the clinical transformation stage

Thus, psychological stress may influence the development of depression by triggering abnormal lipid oxidation

These changes are believed to underlie SCI neuropathic pain in comparison with both able-bodied individuals and those with SCI but no pain [13, 35]