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As ceramide is one of the atherogenic mediators, decreased ceramide resulted in decreased total cholesterol levels in plasma and decreased very low density lipoprotein (VLDL) cholesterol and LDL cholesterol levels in adipocytes (Zhang X

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While the genus Aeromonas includes recognized fish pathogens, the co-dominant genera Clostridium and Cetobacterium are associated with beneficial functions, including enhanced intestinal barrier integrity and suppression of inflammation, which may collectively support host survival in the extreme aquatic environment (Qi et al., 2023