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Figure EV7 BSO sensitivity in the A549shNRF2-BIND rescue system and mechanistic characterization of A-485 treatment in NRF2-dependent NSCLC models

Similarly, it can contribute to the maintenance of a healthy metabolism, leading to more lean muscle mass and strength, decreased body fat, and improved muscle recovery

T cells are isolated from peripheral blood lymphocytes by lysing the red blood cells and depleting the monocytes, for example, by centrifugation through a PERCOLLTM gradient

This work is supported by the National Key Research & Development Program (2022YFC2603900), Beijing Natural Science Foundation (JQ24055), and the National Natural Science Foundation of China (22175189, 52373127)

Glutathione deficiency may promote cancer initiation (by failing to protect DNA from oxidative damage), while elevated glutathione in established tumors may promote cancer progression and treatment resistance (by protecting cancer cells from chemotherapy and radiation) [2][5]