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Category 1 are substances that may be eligible for inclusion on the bulk drug substances list

doi:10.1136/jcp.55.6.475

After 4 weeks of cobalamin treatment, the concentrations of both metabolites decreased, but not significantly, except for borderline P values in the sublingual group ( P = 0.056 and P = 0.052 for homocysteine and MMA concentrations, respectively)