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Description

Histopathological analysis The solid tumor and major organs were harvested from tumor-bearing mice for histological observation by standard H&E and immunofluorescence staining

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However, its application is limited by volatility and poor buccal bioavailability

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Biologists suspect that when the epigenome accumulates too many marks, over time, the signals it sends to cells change dramaticallyand that those new signals produce the effects of aging

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Mechanistically, kefiran (KE) and kefir exo-polysaccharides (KEPS), as well as KPs, inhibit key inflammatory signaling pathways including NF-B, p-MAPK, p-IkB, pp38, and p-JNK, thereby reducing epithelial cell activation, synovitis, macrophage-mediated inflammation, and cytokine overproduction in systemic and localized inflammatory conditions (Chuang et al., 2023

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