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Cell Cycle 12:21632164 Jopling HM, Odell AF, Pellet-Many C, Latham AM, Frankel P, Sivaprasadarao A, Walker JH, Zachary IC, Ponnambalam S (2014) Endosome-to-plasma membrane recycling of VEGFR2 receptor tyrosine kinase regulates endothelial function and blood vessel formation

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The bone and cartilage repair community learned this lesson early: incomplete protocols often produce no measurable benefit, and the same principle applies with even greater force to neurological applications where the biological timelines are longer