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Additionally, strategies targeting iron overload, such as iron chelators, and antioxidants have shown promise in ameliorating granulosa cell ferroptosis and improving reproductive outcomes

N-t-butyl hydroxylamine, a hydrolysis product of -phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts

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These chemical reactions have been extensively characterized for a multitude of foreign chemicals, but they are also critical for the detoxification of endogenous reactive intermediates and, more importantly, for the formation of specific biological mediators (Wang and Ballatori, 1998)