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Pre-clinical animal models also shed new light on possible mechanisms of CIPN, including abnormal cytoskeletal architecture, disrupted axonal transport, mitochondrial dysfunctions, altered neuronal excitability in peripheral neurons, and neuroinflammation

10.1016/j.ejphar.2019.01.006 267 ZhaoJ

Direct and bystander radiation effects: a biophysical model and clinical perspectives

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