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Distant metastasis and progression: Breast cancer metastasis is a complex, multicellular, and highly regulated process involving local invasion of primary tumor cells, epithelial-to-mesenchymal transition, invasion into the bloodstream, survival of tumor cells in the circulatory system, and colonization of secondary distant sites

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Gedam M, et al

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h , The mutational landscape and somatic mutation frequence (SMF) of each GGT gene was analyzed in 105,260 cancer patient samples across 226 non-redundant studies using the cBioPortal platform revealing a low mutation frequency (mean = 0.15%)