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Those S-100 + , GDNF + , or BDNF + cells but not co-expressing human nuclei might be host Schwann cells with an injury-induced repair phenotype characterized by enhanced proliferative, migratory, and invasive capabilities [5, 56], which might have migrated through the damaged epineural barrier to the perineural areas

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While these studies have provided an initial look into the COPD transcriptome, their results primarily relied on the use of lung function tests to define the presence or degree of COPD