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A: AOD-9604 includes an additional tyrosine (Tyr) residue at the N-terminus, making it technically Tyr-hGH Fragment 177-191

K.SwamyI

What they found: Oral AOD-9604 reduced body fat by 18 to 22 % vs placebo, comparable to injection administration No changes in total body weight (because lean mass rose slightly) Decrease in plasma triglycerides by 30 % Decrease in resting free fatty acids (paradoxically, mobilization of fat from depots into oxidation) No GI side effects Why it matters: It suggested that AOD-9604 could work orally , a rare property for a peptide

Kim S, Jin Y, Choi Y, Park T

As discussed, injections are a more reliable, consistent method of maximizing vitamin bioavailability than oral supplements, with a much higher treatment absorption