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Nadjarzadeh A, Shidfar F, Amirjannati N, et al

Molecules 29:2215

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[57] Approval of the original brand-name versions (such as Ozempic) was based on a biologic (recombinant DNA) production process using a genetically-modified yeast ( Saccharomyces cerevisiae ) to produce a precursor to semaglutide, and subsequent chemical processes (protein purification) to create the active ingredient