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Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses

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Addition of the cohesin loader substantially enhanced the RSC1 sliding rate, such that it approached the rate observed with RSC2 (Fig

In this case, overall assessment (WoE) of the general biological plausibility and of the empirical support of KERs was considered as high for this AOP, as well as essentiality, once for this criterion the first four KEs that trigger the AO are also classified as such