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L-carnitine increases ACE1 and decreases ACE2 in lung and muscle tissue, thereby reducing inflammation by converting angiotensin I to angiotensin II, which plays an anti-inflammatory role [26]

The chronic exposure to GH and IGF-1 excess exerts profound effects on carbohydrate and lipid metabolism, primarily through actions on skeletal muscle, liver, and adipose tissue [1, 3]