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Furthermore, glutathione is involved in the regulation of hormonal balance, including the synthesis and metabolism of estrogen and progesterone, which are critical for menstrual cycle regulation and embryo implantation

Cyclic changes in phospholipid content and composition in human endometrium during the menstrual cycle

Heart failure with preserved ejection fraction (HFpEF) accounts for approximately half of all heart failure cases, with patients bearing a high symptomatic burden and physical limitations that impact their daily lives

For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%)