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As the most abundant free amino acid in plasma and muscle, it undergoes rapid turnover and extensive first-pass utilization by enterocytes and immune cells ( Following oral ingestion, plasma concentrations typically rise within 3060 minutes and return toward baseline within several hours due to the high metabolic demand of enterocytes and immune cells

Native LDL induces proliferation of human vascular smooth muscle cells via redox-mediated activation of ERK 1/2 mitogen-activated protein kinases

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doi: 10.1021/cr960065d