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We highlight recent progress in the discovery of selective inhibitors, dual-target inhibitors, allosteric modulators, covalent inhibitors, proteolysis-targeting chimeras (PROTACs), and protein-protein interaction (PPI) modulators

L 1 and L H adjust mutant p53 aggregation by increasing zinc ion levels in cells and promoting interactions between zinc ions and mutant p53

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High temperature induces male sterility via MYB66MYB4Casein kinase I signaling in cotton

Once tumours reached a mean volume of about 200 mm 3 , mice with similarly sized tumours were distributed into treatment cohorts