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Participant protection is the central priority throughout

This may arise from various factors, including individual psychosocial variables (such as anxiety and stress), the open-label design of our study, and the occurrence of spontaneous attacks

[86] Ron Fonger, Flint City Council OKs $2 million for reconnection to Detroit water, Flint Journal /MLive.com, October 12, 2015

Common adverse effects include tachycardia, arrhythmias, and hypertension, and use is contraindicated in patients with idiopathic hypertrophic subaortic stenosis (IHSS), requiring careful monitoring during therapy