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"Typically, hangovers start when alcohol starts to leave our body," says Melanie Betz, M.S., RD, CSR, FAND, aka The Kidney Dietitian

On testing cadence, note that there is no universal evidence-based schedule: the frequency of laboratory monitoring should be individualized according to the therapy being used, underlying medical conditions, treatment response, and current clinical guidelines

Retention in the body: Research has shown that methylcobalamin may retain better in the body than cyanocobalamin

The effect is dose-dependent but plateaus at relatively low concentrations

Those who have more serious symptoms, such as kidney problems, may need strong medications