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While the redox status of TCA enzymes was mainly unchanged (except for malate dehydrogenase at Cys 89 and -ketoglutarate dehydrogenase at Cys 802 ), almost all TCA enzymes were more abundant in tumor cells

Tobacco contains approximately 4,000 chemicals, of which nicotine, carbon monoxide and other components stimulate blood pressure, lead to coronary AS, increase blood and platelet viscosity, reduce the ability to dissolve blood clots and oxygen-carrying capacity of hemoglobin, and even induce ventricular fibrillation, increasing the incidence of cardiovascular events (46, 47)

Neurology 66, 16381643

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