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Moreover, we propose novel, multiomic-based deep learning frameworks that enhance classification accuracy and reproducibilityaddressing key challenges faced in earlier studies and offering new opportunities for precision medicine in thyroid oncology

Notably, a myriad of aging mechanisms, including inflammaging (driven by cellular debris and misfolded proteins), metaflammation (fueled by excessive nutrient intake, dietary patterns, and gut microbiota dynamics), and garbaging (the failure to clear damaged cellular materials), appear to converge on NLRP3-mediated low-grade inflammation