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At each step of the psoriasis molecular pathway, different inflammatory cytokines such as IL-6, IL-17, IL-22, and IL-23 are triggered, on the other side, growth factors such as EGF, VEGF, KGF, and IGF-1, which underscores the central role which predominantly drives epidermal hyperplasia [12, 56, 57]

And so it seems like chronic stress is really bad

Citation: Clemmons DR, Miller S, Mamputu J-C (2017) Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial

J Exp Bot 63:16191636 Khan MIR, Fatma M, Per TS, Anjum NA, Khan NA (2015) Salicylic acid-induced abiotic stress tolerance and underlying mechanisms in plants

[DOI] [PMC free article] [PubMed] [Google Scholar] Bell E