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The ISME Journal

PMID: 10188072

Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3-hydroxyacetanilide, in mouse liver

USA 108 , 36303635 (2011)

It is postulated that glutathione inhibits tyrosinase through three primary mechanisms: direct antioxidant activity, chelation of the copper site within tyrosinase via its thiol group, and disruption of tyrosinases cellular transport to pre-melanosomes