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Vitamin B12, or cobalamin, is essential for many key functions in the body

However, development was discontinued in 2007 after the largest Phase IIb trial failed to demonstrate statistically significant weight loss compared to placebo

The reimbursement of B12 injections has risen to 9.17 for 5 vials (from 7.62)

Health status considerations: Generally healthy adults with physician clearance, individuals without contraindications (pregnancy, active malignancy, severe organ disease), those willing to commit to proper administration protocols and monitoring, and patients who understand the research-purposes-only status and informed consent requirements

Cyanocobalamin is a synthetic form that the body converts to active forms, whilst methylcobalamin is one of the naturally occurring forms