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Published Research Data Quantified findings from peer-reviewed studies on AHK-Cu + GHK-Cu human genes modulated by GHK-Cu in gene expression analysis increase in collagen synthesis observed in fibroblast cultures treated with GHK-Cu increase in VEGF expression in dermal papilla cells exposed to AHK-Cu reduction in TNF-alpha inflammatory markers in GHK-Cu treated tissue models verified purity by HPLC analysis in every Stemcode batch with published COA collagen and ECM-related genes upregulated by GHK-Cu in connectivity map data Published Research Studies on AHK-Cu + GHK-Cu 2018 Regenerative and protective actions of the GHK-Cu peptide in the light of new gene data Int J Mol Sci 2015 GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration BioMed Res Int 2012 GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes Cosmetics 2008 The human tri-peptide GHK and tissue remodeling J Pept Sci 2007 The effect of tripeptide-copper complex on human hair growth in vitro Arch Pharm Res Why Research Peptides All comparisons reflect general industry practices

Because these models require their participating practitioners to report on quality and cost performance metrics that are aligned or overlap with the Value in Primary Care MVP, we proposed that requiring these practitioners to report the Value in Primary Care MVP for purposes of billing for APCM services would be substantially duplicative

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