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Choose whichever site is most comfortable and convenient for you, and rotate between both for optimal long-term tissue health

The primary preclinical evidence comes from mouse studies showing reduced body weight and adipose mass in diet-induced obese mice (2018), improved grip strength in aged mice (2024), and beneficial microbiome changes when combined with caloric restriction (2022)

The hype around the other forms of B12 is mostly propaganda from the supplement industry

Intramuscular These injections typically have better results and inject the medicine directly into the muscle, which is then absorbed by the surrounding muscle immediately

Since it's water-soluble, your body usually excretes excess amounts through urine