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Durak et al., [21], demonstrated that superoxide dismutase (SOD) activity was elevated in the gastric mucosa of patients with acute peptic ulcer reflecting a possible role for ROS in the stimulation of endogenous antioxidant enzymes in the acute phase of the disease

Protective pathways included the S-adenosyl-L-methionine (SAMe) cycle, the same methylation pathway relevant to MTHFR variants, suggesting that methylation status may independently affect auditory neuroinflammation [2]

[DOI] [PubMed] [Google Scholar] 382.Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, et al

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In contrast, neural cells may rely on the Nrf2-SLC7A11 axis to maintain antioxidant capacity, so quercetin protects cells by activating this axis