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When the homeostatic balance of copper ion levels is disrupted, such as through excess copper ions, this imbalance can trigger cellular toxicity and induce cell death via various pathways (15)

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Dietary requirements The daily requirement of vitamin B 12 has been set at 2.4 g, but higher amounts 4 to 7 g per day which are common in persons who eat meat or take a daily multivitamin, are associated with lower methylmalonic acid values

Additionally, riboflavin is often added to processed breakfast cereals and is used as a yellow-orange food coloring