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doi: 10.1158/1535-7163.MCT-19-0079 55 OBrienMet al

Fang et al.'s research demonstrated that ferroptosis occurs in a mouse model of myocardial I/R injury [203]

Conversely, genetic knockdown of TXNDC12 enhances ferroptosis sensitivity, leading to increased lipid peroxidation both i n vitro and in vivo [134, 135]