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IGF-1 LR3 primarily exerts its effects through activation of the IGF-1 receptor (IGF-1R), a transmembrane tyrosine kinase receptor expressed in muscle, bone, connective tissue, and various other cell types

The TCA cycle remains active, and amino acids are transported by SLC1A5

In spermatocytes, the ATP pathway shifts from glucose utilization to lactic acid and pyruvate mainly through OXPHOS [101]

doi: 10.3389/fpls.2013.00314 Received 30 May 2013 Accepted 26 July 2013 Published 16 August 2013 Volume 4 - 2013 Edited by Emmanuel Baudouin, Universit Pierre et Marie Curie - Paris 6, France Reviewed by Vasileios Fotopoulos, Cyprus University of Technology, Cyprus

The release of DAMPs is conducive to augmenting the immune response activation