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Description

Effects of meal timing on tumor progression in mice

Isoalantolactone inhibits IKKbeta kinase activity to interrupt the NF-kappaB/COX-2-mediated signaling cascade and induces apoptosis regulated by the mitochondrial translocation of cofilin in glioblastoma

Biochemically, it is marked by disrupted iron metabolism, accumulation of lipid hydroperoxides (LPO), and depletion of intracellular glutathione (GSH)