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Legius syndrome is of autosomal dominant transmission and is characterized by the presence of CaLS and/or freckles, which are occasionally associated with macrocephaly, lipomas, Noonan phenotype, and/or learning difficulties.23 Often, these patients meet sufficient pigmentary criteria for diagnosis of NF1, but in Legius syndrome the presence of Lisch nodules, neurofibromas, central nervous system tumors, and NF1 gene mutations are specifically excluded

The number of sessions varies depending on individual needs, but most patients undergo a series of treatments over several weeks

Disease progression often reflects either an inability to mount such a coordinated response or a maladaptive over-activation that disrupts homeostatic balance

Obesity is linked to deficiencies, too

Due to the multidirectional effect of ingredients present in Cornelian cherry, the application of Cornus mas leaves as a supplement additive would warrant plenty of positive impacts on the human organism